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TU-Clausthal Institute for Separation and Process Technology

Downstream processing

This research focus includes the development of downstream processing of biomolecules such as recombinant protein and antibody purifications as well as isomer and enantiomer separations from fine chemicals and the pharmaceutical industry. The aim is to model the separation of substances in conventional and monolithic media, taking into account the influence of mass transport processes and the experimental comparison of monoliths and particles.

Eine Darstellung eines Proteinmodells mit bunten Bändern auf schwarzem Hintergrund. Die Bänder symbolisieren die dreidimensionale Struktur des Proteins, wobei verschiedene Farben unterschiedliche Sekundärstrukturen anzeigen.

Research projects:

Downstream of downstream processing

Integration of material design and process development methods for the downstream processing of recombinant proteins and MABs

Development of design methods for process development in thermal separation technology and downstream processing