Institute for Separation and Process Technology > Research > Process intensification > Development of design methods for ...

Development of design methods for the process development of thermal separation technology and down-stream processing

A new topic of the ITVP is the development of design methods for the targeted, such as groups of molecules, isomers, enantiomers, diastereomere, SunFuels, phytoextrakts, plant made pharmaceuticals, peptides, proteins, monoclonal antibodies.

Growing economic pressure and increasing limitations of healthcare systems require extensive process improvements. The aim of this work is to develope new efficient design methods, processes and equipment which allow new products to be effectively produced. Furthermore, this new know-How can be employed to realize existing optimization potentials in the production of synthetic and biotechnological pharmaceuticals and fine chemicals.

The field of interest is as follows:

    1. Design, construction and commissioning of

        a) a mini-plant as well as of

        b) a micro (-pilot) plant

    2. Efficient methods for process development and intensification of Downstream Processing in

        a) a mini-plant and

        b) a micro (-pilot) plant

 

For this purpose all necessary unit operations of thermal separation technology and Downstream Processing (solid-liquid extraction, liquid-liquid extraction, distillation, adsorption, chromatography, ion-exchange, seelective-, ultra- and diafiltration membranes, crystalization/precipitation with filtration and drying/lyophilization) shall be investigated.

Mini- and micro-plants for the separate unit operations have to be designed, manufactured, measured and modelled. Existing contacts/cooperations to the industry in different fields of expertise allow for interdisciplinary cooperation work.

 

Contact person: Dipl.-Ing. Jan Kristof Eggersglüß

 

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